Buy Artesunate 50mg Tablet Online At Best Price

What is Artesunate 50mg Tablet?

artesunate is a water-soluble hemisuccinate derivative of artemisinin. It is unstable in neutral solution and the injectable formulation must be prepared immediately before use in 5% (w/v) sodium bicarbonate solution to produce the salt sodium artesunate. After parenteral administration, it is rapidly hydrolysed to the active metabolite dihydroartemisinin. The oral formulation is probably hydrolysed completely before entering the systemic circulation.

artesunate 50mg toxicity has been reported to clear fever in patients with severe falciparum malaria 16-25 hours after parenteral administration

Side Effects

Major & minor Artesunate 50mg side effect

  • Transient And Reversible Reticulocytopaenia,
  • Drug Fever,
  • Rash,
  • Bradycardia,
  • Transient 1st-Degree Heart Block
  • Reversible Elevation Of Serum Transaminases

Dosage and administration

Oral administration

Adults and children over 6 months: 5 mg/kg orally on the first day followed by 2.5 mg/kg on the second and third days in combination with mefloquine (15 mg/kg) in a single dose on the second day. In a few areas, a higher dose (25 mg/kg) of mefloquine may be required for a cure to be obtained.

Parenteral administration

The powder for injection should be reconstituted with 5% sodium bicarbonate and diluted in an equal volume of physiological saline or 5% (w/v) glucose. It should be administered immediately by either intravenous or intramuscular injection.

A loading dose of 2 mg/kg should be followed by 1 mg/kg after 4 hours and 24 hours. Thereafter a dose of 1 mg/kg should be given daily until the patient is able to tolerate oral artesunate spc or for a maximum of 7 days.


Artesunate contraindications in Oral artesunate should not be used during the first trimester of pregnancy.


Parenteral artesunate injection should be used for the treatment of severe falciparum malaria only where there is evidence that the antimalarial efficacy of quinine is declining.

The powder for injection is difficult to dissolve and care should be taken to ensure that it is completely dissolved before parenteral administration. It should always be used immediately following reconstitution. If the solution is cloudy or a precipitate is present, the parenteral preparation should be discarded.

Use in pregnancy

Little experience has been gained with the use of artesunate in pregnancy  but the parenteral preparation should not be withheld if it is considered life-saving to the mother.


Tablets and powder for injection should be stored in tightly closed containers, protected from light.

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