what is dipivefrin ?

Accuretic is used for:

Treating high blood pressure. It may also be used for other conditions as determined by your doctor.

Accuretic is an angiotensin-converting enzyme (ACE) inhibitor and thiazide diuretic combination. It works by causing blood vessels to relax (widen) and increasing the excretion of excess fluid, which lowers blood pressure.

Do not use Accuretic if:

you are allergic to any ingredient in Accuretic or any other sulfonamide medicine (eg, glyburide, probenecid, sulfamethoxazole)

you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) caused by treatment with an ACE inhibitor

  • you are pregnant
  • you have severe kidney problems or are unable to urinate
  • you are taking a medicine that contains aliskiren and you also have diabetes or kidney problems. Check with your doctor or pharmacist if you are not sure if a medicine you take contains aliskiren
  • you are taking dextran sulfate, dofetilide, or ketanserin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Accuretic:

Some medical conditions may interact with Accuretic. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are able to become pregnant
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of heart problems (eg, heart failure, aortic stenosis), blood vessel problems (eg, in the brain or heart), blood flow problems, bone marrow problems, kidney problems (eg, renal artery stenosis), liver problems, diabetes, or angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness)
  • if you have a history of a stroke, recent heart attack, or kidney transplant
  • if you have an autoimmune disease (eg, rheumatoid arthritis, lupus, scleroderma)
  • if you are dehydrated or have low blood volume
  • if you have high potassium levels, low blood sodium levels, high blood cholesterol or lipid levels, gout, or are on a low-salt (sodium) diet
  • if you are receiving treatments to reduce sensitivity to bee or wasp stings
  • if you are scheduled to have surgery or to receive anesthesia, have recently had a certain type of nerve surgery (sympathectomy), or are on dialysis
  • if you have never taken another medicine for high blood pressure

Dextran sulfate, digoxin, dofetilide, ketanserin, lithium, or thiopurines (eg, azathioprine) because the risk of their side effects may be increased by Accuretic

Insulin, oral hypoglycemics (eg, glyburide), or tetracycline because their effectiveness may be decreased by Accuretic

This may not be a complete list of all interactions that may occur. Ask your health care provider if Accuretic may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Accuretic:

Use Accuretic as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Accuretic by mouth with or without food.

Accuretic may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

If you are taking a tetracycline antibiotic, a quinolone antibiotic (eg, ciprofloxacin, levofloxacin), or colestipol or cholestyramine for high cholesterol, ask your doctor or pharmacist how to take it with Accuretic. This product contains magnesium, which can interfere with absorption of these medicines.

Take Accuretic on a regular schedule to get the most benefit from it.

Taking Accuretic at the same time each day will help you remember to take it.

Continue to take Accuretic even if you feel well. Do not miss any doses.

If you miss a dose of Accuretic, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Accuretic.

Important safety information:

Accuretic may cause drowsiness, dizziness, light-headedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Accuretic with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

Accuretic may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Report any light-headedness or fainting to your doctor immediately. Your risk of light-headedness or fainting may be increased if you experience diarrhea, vomiting, or excessive sweating, if you do not drink enough fluids, or if you are on a low-salt (sodium) diet.

Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel “normal.” Tell your doctor if you develop any new symptoms.

Accuretic has magnesium in it. Before you start any new medicine, check the label to see if it has magnesium in it too. If it does or if you are not sure, check with your doctor or pharmacist.

Accuretic may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Accuretic. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

Possible side effects of Accuretic:

  • Cough producing mucus
  • diarrhea
  • difficulty breathing
  • tightness in the chest
  • Blurred vision
  • confusion
  • decreased urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • increase in heart rate
  • irregular heartbeat
  • muscle cramps or pain
  • numbness, tingling, pain, or weakness in the hands or feet
  • rapid breathing
  • seizures
  • sunken eyes

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